{ "_id": "6a487e98e06c18f0a653da1e", "Package": "PRIMEplus", "Title": "Study Design for Immunotherapy Clinical Trials", "Version": "1.0.16", "Date": "2024-01-09", "Authors@R": "c(person(\"Zhenzhen\", \"Xu\", role=\"aut\", email=\"Zhenzhen.Xu@fda.hhs.gov\"),\nperson(\"Yongsoek\", \"Park\", role=\"aut\", email=\"yongpark@pitt.edu\"),\nperson(\"Zhu\", \"Bin\", role=\"aut\", email=\"bin.zhu@nih.gov\"),\nperson(\"Bill\", \"Wheeler\", role=\"cre\", email=\"wheelerb@imsweb.com\"))", "Description": "Perform sample size, power calculation and subsequent\nanalysis for Immuno-oncology (IO) trials composed of responders\nand non-responders.", "Maintainer": "Bill Wheeler ", "License": "GPL-2", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-07-04 03:25:49 UTC", "User": "root" }, "Author": "Zhenzhen Xu [aut], Yongsoek Park [aut], Zhu Bin [aut], Bill\nWheeler [cre]", "Repository": "https://wheelerb.r-universe.dev", "Date/Publication": "2024-01-11 02:40:14 UTC", "RemoteUrl": "https://github.com/cran/PRIMEplus", "RemoteRef": "HEAD", "RemoteSha": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "_user": "wheelerb", "_type": "src", "_file": "PRIMEplus_1.0.16.tar.gz", "_fileid": "https://r2.ropensci.org/90e587db7417751476e09b525a47f59da9a1f4782b566433fa829efa7652283c", "_filesize": 147983, "_sha256": "90e587db7417751476e09b525a47f59da9a1f4782b566433fa829efa7652283c", "_expires": "2026-10-12T03:31:34.000Z", "_created": "2026-07-04T03:25:49.000Z", "_published": "2026-07-04T03:31:35.995Z", "_jobs": [ { "job": 85098979752, "time": 159, "config": "linux-devel-arm64", "r": "4.7.0", "check": "OK", "artifact": "8077890739" }, { "job": 85098979754, "time": 182, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "8077892962" }, { "job": 85098979778, "time": 134, "config": "linux-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "8077887983" }, { "job": 85098979753, "time": 163, "config": "linux-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "8077890771" }, { "job": 85098979760, "time": 84, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "8077881897" }, { "job": 85098979764, "time": 241, "config": "macos-oldrel-x86_64", "r": "4.5.3", "check": "OK", "artifact": "8077899096" }, { "job": 85098979761, "time": 91, "config": "macos-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "8077882647" }, { "job": 85098979757, "time": 314, "config": "macos-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "8077907540" }, { "job": 85098805089, "time": 152, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "8077872137" }, { "job": 85098979751, "time": 113, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "8077885328" }, { "job": 85098979749, "time": 107, "config": "windows-devel", "r": "4.7.0", "check": "OK", "artifact": "8077884530" }, { "job": 85098979767, "time": 98, "config": "windows-oldrel", "r": "4.5.3", "check": "OK", "artifact": "8077883440" }, { "job": 85098979750, "time": 94, "config": "windows-release", "r": "4.6.1", "check": "OK", "artifact": "8077883048" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956", "_status": "success", "_upstream": "https://github.com/cran/PRIMEplus", "_commit": { "id": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "author": "Bill Wheeler ", "committer": "cran-robot ", "message": "version 1.0.16\n", "time": 1704940814 }, "_maintainer": { "name": "Bill Wheeler", "email": "wheelerb@imsweb.com", "login": "wheelerb", "description": "", "uuid": 33498685 }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 3.5", "role": "Depends" }, { "package": "survival", "role": "Depends" }, { "package": "msm", "role": "Depends" } ], "_owner": "cran", "_selfowned": true, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 0, "_contributors": [ { "user": "wheelerb", "count": 1, "uuid": 33498685 } ], "_userbio": { "uuid": 33498685, "type": "user", "name": "wheelerb", "followers": 1 }, "_downloads": { "count": 245, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/PRIMEplus" }, "_searchresults": 0, "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/PRIMEplus.html", "manual.pdf" ], "_realowner": "wheelerb", "_cranurl": false, "_releases": [ { "version": "1.0.16", "date": "2024-01-10" } ], "_exports": [ "generate_data", "getHazard", "PRIMEplus.EM", "PRIMEplus.LRT", "PRIMEplus.Power", "PRIMEplus.ReRand.LRT", "PRIMEplus.SampleSize" ], "_datasets": [ { "name": "data", "title": "Data for examples", "object": "data", "file": "data.rda", "class": [ "data.frame" ], "fields": [ "id", "trt", "D1", "D2", "D3", "tau", "enroll_time", "time_to_event", "event_status", "X", "t1" ], "rows": 300, "table": true, "tojson": true } ], "_help": [ { "page": "PRIMEplus-package", "title": "Study design for immunotherapy clinical trials", "topics": [ "PRIMEplus" ] }, { "page": "data", "title": "Data for examples", "topics": [ "data" ] }, { "page": "generate_data", "title": "Simulated data", "topics": [ "generate_data" ] }, { "page": "getHazard", "title": "Compute initial estimates for the baseline hazard", "topics": [ "getHazard" ] }, { "page": "PRIMEplus.EM", "title": "EM algorithm", "topics": [ "PRIMEplus.EM" ] }, { "page": "PRIMEplus.LRT", "title": "Likelihood Ratio Test", "topics": [ "PRIMEplus.LRT" ] }, { "page": "PRIMEplus.power", "title": "Power", "topics": [ "PRIMEplus.Power" ] }, { "page": "PRIMEplus.ReRand.LRT", "title": "Randomization Test", "topics": [ "PRIMEplus.ReRand.LRT" ] }, { "page": "PRIMEplus.SampleSize", "title": "Sample Size", "topics": [ "PRIMEplus.SampleSize" ] } ], "_rundeps": [ "cli", "expm", "generics", "glue", "lattice", "lifecycle", "magrittr", "Matrix", "msm", "mvtnorm", "pillar", "pkgconfig", "rlang", "survival", "tibble", "utf8", "vctrs" ], "_score": 1, "_indexed": true, "_nocasepkg": "primeplus", "_universes": [ "wheelerb" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "1.0.16", "date": "2026-07-04T03:28:22.000Z", "distro": "resolute", "arch": "aarch64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/5b57fbda8b88631cf249e10313c086d8ed525b39044a2495756d88588c06b98a", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.7.0", "os": "linux", "version": "1.0.16", "date": "2026-07-04T03:28:34.000Z", "distro": "resolute", "arch": "x86_64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/85bdad656f12bb8ab0372d8fb8a269b6d5833ccdd865a043818c35395996dbc1", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.6.1", "os": "linux", "version": "1.0.16", "date": "2026-07-04T03:27:58.000Z", "distro": "resolute", "arch": "aarch64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/78e4ca01f1c7947ef69680b58fc63742ef0bd9e358aed650e508edf24610cacf", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.6.1", "os": "linux", "version": "1.0.16", "date": "2026-07-04T03:28:10.000Z", "distro": "resolute", "arch": "x86_64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/69200bbbb79b875d417de774c933d6961d71461ad7818a7478867261fb70953c", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.5.3", "os": "mac", "version": "1.0.16", "date": "2026-07-04T03:27:08.000Z", "arch": "aarch64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/3d91b9bd21e9c3ec29b6352a2a1d5627ca9d0e984c72dcb8721a125fc23f8280", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.5.3", "os": "mac", "version": "1.0.16", "date": "2026-07-04T03:28:58.000Z", "arch": "x86_64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/5fb774d1e60d45cce2c3ba126db280a1f3ae7afa4d821b903bb9f07b0a6df943", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.6.1", "os": "mac", "version": "1.0.16", "date": "2026-07-04T03:27:10.000Z", "arch": "aarch64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/25b4dc70f5751459cf1df46ba268eb49e49a656a497e5092bcbebf0af2901fe5", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.6.1", "os": "mac", "version": "1.0.16", "date": "2026-07-04T03:30:05.000Z", "arch": "x86_64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/bb7b3a9c2ead31b3e17751930b7c2e4eecfb49dcb9b11582ad08e17d066e2003", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.6.0", "os": "wasm", "version": "1.0.16", "date": "2026-07-04T03:27:58.000Z", "arch": "emscripten", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/0955a3eb0ff887b7b9377e94ada701f5d96da9ba202cda6d9dcb575c64bcee81", "status": "success", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.7.0", "os": "win", "version": "1.0.16", "date": "2026-07-04T03:27:06.000Z", "arch": "x86_64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/04c5f5bf439c413afe1b26123e3d40cf0e8c38628e92fe5420e618fe751288e9", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.5.3", "os": "win", "version": "1.0.16", "date": "2026-07-04T03:26:55.000Z", "arch": "x86_64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/ac57b8b78c0c490e4476437eb5f699db844a778f5a93dffdab746e973e5cfcc1", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" }, { "r": "4.6.1", "os": "win", "version": "1.0.16", "date": "2026-07-04T03:26:55.000Z", "arch": "x86_64", "commit": "6ea68294404ed2446ca40ab64350bfbe0b6accc9", "fileid": "https://r2.ropensci.org/5479341158b6aab3049d42fa2bcd6a7ac4925d38819f98452467f32258bbb6c9", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/wheelerb/actions/runs/28693415956" } ] }